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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: P04179




USC-OGP 2-DE database:  P04179


P04179


General information about the entry
View entry in simple text format
Entry nameSODM_HUMAN
Primary accession numberP04179
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Superoxide dismutase [Mn], mitochondrial; EC=1.15.1.1; Flags: Precursor;.
Gene nameName=SOD2
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_6-11 {PLATELET 6-11}
Homo sapiens (Human)
PLATELET_6-11
  map experimental info
 
PLATELET_6-11

MAP LOCATIONS:
pI=6.69; Mw=22601
pI=6.98; Mw=22469
pI=6.91; Mw=22404



UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=6.93; Mw=22446

Cross-references
UniProtKB/Swiss-ProtP04179; SODM_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameSODM_HUMAN
Primary accession numberP04179
Secondary accession number(s) B2R7R1 B3KUK2 B4DL20 B4E3K9 E1P5A9 P78434 Q16792 Q5TCM1 Q96EE6 Q9P2Z3
Sequence was last modified on April 1, 1990 (version 2)
Annotations were last modified on March 15, 2017 (version 208)
Name and origin of the protein
DescriptionRecName: Full=Superoxide dismutase [Mn], mitochondrial; EC=1.15.1.1; Flags: Precursor;
Gene nameName=SOD2
Encoded onName=SOD2
Keywords3D-structure; Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Manganese; Metal-binding; Mitochondrion; Nitration; Oxidoreductase; Polymorphism; Reference proteome; Transit peptide.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLX59445; CAA42066.1; -; mRNA
EMBLY00472; CAA68533.1; -; mRNA
EMBLY00985; CAA68791.1; -; mRNA
EMBLX07834; CAA30687.1; -; mRNA
EMBLM36693; AAA36622.1; -; mRNA
EMBLX15132; CAA33228.1; -; mRNA
EMBLX14322; CAA32502.1; -; mRNA
EMBLS77127; AAD14248.1; ALT_SEQ; Genomic_DNA
EMBLBT006967; AAP35613.1; -; mRNA
EMBLAY267901; AAP03428.1; -; Genomic_DNA
EMBLAK097395; BAG53464.1; -; mRNA
EMBLAK296809; BAG59382.1; -; mRNA
EMBLAK304766; BAG65521.1; -; mRNA
EMBLAK313082; BAG35908.1; -; mRNA
EMBLAL135914; CAI21845.1; -; Genomic_DNA
EMBLCH471051; EAW47630.1; -; Genomic_DNA
EMBLCH471051; EAW47631.1; -; Genomic_DNA
EMBLBC012423; AAH12423.1; -; mRNA
CCDSCCDS34564.1; -. [P04179-2]; .
CCDSCCDS5265.1; -. [P04179-1]; .
CCDSCCDS83141.1; -. [P04179-4]; .
CCDSCCDS83143.1; -. [P04179-3]; .
PIRS13162; DSHUN; .
RefSeqNP_000627.2; NM_000636.3; .
RefSeqNP_001019636.1; NM_001024465.2; .
RefSeqNP_001019637.1; NM_001024466.2; .
RefSeqNP_001309743.1; NM_001322814.1; .
RefSeqNP_001309744.1; NM_001322815.1; .
RefSeqNP_001309746.1; NM_001322817.1. [P04179-4]; .
RefSeqNP_001309748.1; NM_001322819.1. [P04179-4]; .
RefSeqNP_001309749.1; NM_001322820.1. [P04179-4]; .
UniGeneHs.487046; -; .
PDB1AP5; X-ray; 2.20 A; A/B=25-222
PDB1AP6; X-ray; 1.90 A; A/B=25-222
PDB1EM1; X-ray; 2.13 A; A/B=25-222
PDB1JA8; X-ray; 2.12 A; A/B=25-222
PDB1LUV; X-ray; 1.85 A; A/B=25-222
PDB1LUW; X-ray; 2.30 A; A/B=25-222
PDB1MSD; X-ray; 3.20 A; A/B=25-222
PDB1N0J; X-ray; 2.20 A; A/B=25-222
PDB1N0N; X-ray; 1.82 A; A/B=25-222
PDB1PL4; X-ray; 1.47 A; A/B/C/D=25-222
PDB1PM9; X-ray; 1.70 A; A/B=25-222
PDB1QNM; X-ray; 2.30 A; A/B=25-222
PDB1SZX; X-ray; 1.95 A; A/B=25-222
PDB1VAR; X-ray; 2.50 A; A/B=25-222
PDB1XDC; X-ray; 1.85 A; A/B=25-222
PDB1XIL; X-ray; 1.53 A; A/B=25-222
PDB1ZSP; X-ray; 1.90 A; A/B=25-222
PDB1ZTE; X-ray; 1.85 A; A/B/C/D=25-222
PDB1ZUQ; X-ray; 2.00 A; A/B=25-222
PDB2ADP; X-ray; 2.40 A; A=25-222
PDB2ADQ; X-ray; 2.40 A; B=25-222
PDB2GDS; X-ray; 2.30 A; A/B/C/D=25-222
PDB2P4K; X-ray; 1.48 A; A/B/C/D=25-222
PDB2QKA; X-ray; 2.20 A; A/C=25-220
PDB2QKC; X-ray; 2.30 A; A/C=25-220
PDB3C3S; X-ray; 2.50 A; A/B=25-222
PDB3C3T; X-ray; 2.20 A; A/B=25-222
PDBsum1AP5; -; .
PDBsum1AP6; -; .
PDBsum1EM1; -; .
PDBsum1JA8; -; .
PDBsum1LUV; -; .
PDBsum1LUW; -; .
PDBsum1MSD; -; .
PDBsum1N0J; -; .
PDBsum1N0N; -; .
PDBsum1PL4; -; .
PDBsum1PM9; -; .
PDBsum1QNM; -; .
PDBsum1SZX; -; .
PDBsum1VAR; -; .
PDBsum1XDC; -; .
PDBsum1XIL; -; .
PDBsum1ZSP; -; .
PDBsum1ZTE; -; .
PDBsum1ZUQ; -; .
PDBsum2ADP; -; .
PDBsum2ADQ; -; .
PDBsum2GDS; -; .
PDBsum2P4K; -; .
PDBsum2QKA; -; .
PDBsum2QKC; -; .
PDBsum3C3S; -; .
PDBsum3C3T; -; .
ProteinModelPortalP04179; -; .
SMRP04179; -; .
BioGrid112531; 38; .
IntActP04179; 20; .
MINTMINT-5002369; -; .
STRING9606.ENSP00000356022; -; .
DrugBankDB04436; 3-Fluorotyrosine; .
DrugBankDB03297; Benzylsulfinic Acid; .
Allergome784; Hom s MnSOD; .
iPTMnetP04179; -; .
PhosphoSitePlusP04179; -; .
SwissPalmP04179; -; .
BioMutaSOD2; -; .
DMDM134665; -; .
DOSAC-COBS-2DPAGEP04179; -; .
OGPP04179; -; .
SWISS-2DPAGEP04179; -; .
UCD-2DPAGEP04179; -; .
EPDP04179; -; .
MaxQBP04179; -; .
PaxDbP04179; -; .
PeptideAtlasP04179; -; .
PRIDEP04179; -; .
TopDownProteomicsP04179-1; -. [P04179-1]; .
TopDownProteomicsP04179-2; -. [P04179-2]; .
DNASU6648; -; .
EnsemblENST00000546087; ENSP00000442920; ENSG00000112096. [P04179-4]; .
GeneID6648; -; .
KEGGhsa:6648; -; .
UCSCuc003qsf.6; human. [P04179-1]; .
CTD6648; -; .
DisGeNET6648; -; .
GeneCardsSOD2; -; .
HGNCHGNC:11180; SOD2; .
HPACAB002013; -; .
HPAHPA001814; -; .
MalaCardsSOD2; -; .
MIM147460; gene; .
MIM612634; phenotype; .
neXtProtNX_P04179; -; .
OpenTargetsENSG00000112096; -; .
PharmGKBPA36017; -; .
eggNOGKOG0876; Eukaryota; .
eggNOGCOG0605; LUCA; .
GeneTreeENSGT00390000011877; -; .
HOGENOMHOG000013583; -; .
HOVERGENHBG004451; -; .
InParanoidP04179; -; .
KOK04564; -; .
PhylomeDBP04179; -; .
TreeFamTF105132; -; .
BioCycMetaCyc:HS03515-MONOMER; -; .
BRENDA1.15.1.1; 2681; .
ReactomeR-HSA-3299685; Detoxification of Reactive Oxygen Species; .
ReactomeR-HSA-8862803; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; .
SIGNORP04179; -; .
ChiTaRSSOD2; human; .
EvolutionaryTraceP04179; -; .
GeneWikiSOD2; -; .
GenomeRNAi6648; -; .
PROPR:P04179; -; .
ProteomesUP000005640; Chromosome 6; .
BgeeENSG00000112096; -; .
CleanExHS_SOD2; -; .
ExpressionAtlasP04179; baseline and differential; .
GenevisibleP04179; HS; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0005759; C:mitochondrial matrix; TAS:BHF-UCL; .
GOGO:0005739; C:mitochondrion; IDA:BHF-UCL; .
GOGO:0042802; F:identical protein binding; IPI:IntAct; .
GOGO:0030145; F:manganese ion binding; IDA:UniProtKB; .
GOGO:0004784; F:superoxide dismutase activity; IDA:UniProtKB; .
GOGO:0001315; P:age-dependent response to reactive oxygen species; IMP:UniProtKB; .
GOGO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL; .
GOGO:0043524; P:negative regulation of neuron apoptotic process; IGI:BHF-UCL; .
GOGO:1902176; P:negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; IMP:BHF-UCL; .
GOGO:0032364; P:oxygen homeostasis; IMP:BHF-UCL; .
GOGO:0051289; P:protein homotetramerization; IPI:UniProtKB; .
GOGO:0008217; P:regulation of blood pressure; ISS:BHF-UCL; .
GOGO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB; .
GOGO:0001836; P:release of cytochrome c from mitochondria; ISS:BHF-UCL; .
GOGO:0019430; P:removal of superoxide radicals; IMP:BHF-UCL; .
GOGO:0000302; P:response to reactive oxygen species; TAS:Reactome; .
GOGO:0000303; P:response to superoxide; IMP:BHF-UCL; .
GOGO:0006801; P:superoxide metabolic process; IDA:UniProtKB; .
GOGO:0003069; P:vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure; ISS:BHF-UCL; .
InterProIPR001189; Mn/Fe_SOD; .
InterProIPR019833; Mn/Fe_SOD_BS; .
InterProIPR019832; Mn/Fe_SOD_C; .
InterProIPR019831; Mn/Fe_SOD_N; .
PfamPF02777; Sod_Fe_C; 1; .
PfamPF00081; Sod_Fe_N; 1; .
PIRSFPIRSF000349; SODismutase; 1; .
PRINTSPR01703; MNSODISMTASE; .
SUPFAMSSF46609; SSF46609; 1; .
SUPFAMSSF54719; SSF54719; 1; .
PROSITEPS00088; SOD_MN; 1; .



USC-OGP 2-DE database image


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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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